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mouse MDK shRNA silencing Adenovirus

Name 
Ad-m-MDK-shRNA
Cat No 
shADV-264418
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Mdk.

shADV-264418
Ad-m-MDK-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mdk (midkine). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Mek; MK
Description (Vector)
Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity).
Gene ID
17242
Gene Name (Vector)
midkine
Gene Symbol
Mdk
ORF Size (aa)
423
RefSeq ID
NM_010784
RefSeq Synonyms
NM_010784, NM_001291483, NM_001291482, NM_001291481, NM_001012336, NM_001012335, BC012244,
Species
mouse
UniGene ID
Mm.906

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.