human MDH2 shRNA silencing AAV

Name 
AAV-h-MDH2-shRNA
Cat No 
shAAV-215217
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MDH2.

shAAV-215217
AAV-h-MDH2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MDH2 (malate dehydrogenase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
M-MDH; MDH; MGC:3559; MOR1
Description (Vector)
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.
Gene ID
4191
Gene Name (Vector)
malate dehydrogenase 2
Gene Symbol
MDH2
HGNC ID
HGNC:6971
ORF Size (aa)
1017
ORF Size (bp)
1017 bp
RefSeq ID
NM_005918
RefSeq Synonyms
NM_005918, NM_001282404, NM_001282403, BC001917,
Species
human
UniGene ID
Hs.520967

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.