human MAPK6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MAPK6.
shAAV-214979
AAV-h-MAPK6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MAPK6 (mitogen-activated protein kinase 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ERK3; ERK-3; extracellular signal-regulated kinase 3; extracellular signal-regulated kinase, p97; HsT17250; MAP kinase 6; MAP kinase isoform p97; MAPK 6; mitogen-activated protein kinase 6; p97MAPK; p97-MAPK; PRKM6; protein kinase, mitogen-activated 5; protein kinase, mitogen-activated 6
Description (eCommerce)
ERK3 (extracellular signal-regulated kinase 3) is a member of the Ser/Thr protein kinase family and mitogen-activated protein kinases (MAP kinases). ERK3 is an atypical MAP kinase that likely plays a key role in development.
Description (Vector)
MAPK6 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
Gene ID
5597
Gene Name (eCommerce)
mitogen-activated protein kinase 6
Gene Name (Vector)
mitogen-activated protein kinase 6
Gene Symbol
MAPK6
HGNC ID
HGNC:6879
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2166
ORF Size (bp)
2166 bp
Protein Name (eCommerce)
Mitogen-activated protein kinase 6
RefSeq ID
NM_002748
RefSeq Synonyms
NM_002748, BC035492,
Research Areas
Cell Cycle,Cytoskeleton,Insulin Signaling,Kinase/Phosphatase,MAPK Signaling,Signal Transduction,VEGF Signaling
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
ERK3 (extracellular signal-regulated kinase 3) is a member of the Ser/Thr protein kinase family and mitogen-activated protein kinases (MAP kinases). ERK3 is an atypical MAP kinase that likely plays a key role in development.
UniGene ID
Hs.411847
UniProt ID (eCommerce)
Q16659
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.