mouse MAPK6 shRNA silencing AAV

Name 
AAV-m-MAPK6-shRNA
Cat No 
shAAV-264223
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Mapk6.

shAAV-264223
AAV-m-MAPK6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Mapk6 (mitogen-activated protein kinase 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610021I23Rik; D130053K17Rik; Erk3; Mapk4; Mapk63; Prkm4; Prkm6
Description (Vector)
Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).
Gene ID
50772
Gene Name (Vector)
mitogen-activated protein kinase 6
Gene Symbol
Mapk6
ORF Size (aa)
2163
ORF Size (bp)
2163 bp
RefSeq ID
NM_015806
RefSeq Synonyms
NM_027418, NM_015806, BC100385, BC052420, BC048779,
Species
mouse
UniGene ID
Mm.477772

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.