human MAP3K14 shRNA silencing AAV

Name
AAV-h-MAP3K14-shRNA

Cat No
shAAV-214928

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MAP3K14.

shAAV-214928

AAV-h-MAP3K14-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAP3K14 (mitogen-activated protein kinase kinase kinase 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FTDCR1B; HS; HSNIK; NIK

Description (Vector)

MAP3K14 encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Gene ID

9020

Gene Name (Vector)

mitogen-activated protein kinase kinase kinase 14

Gene Symbol

MAP3K14

HGNC ID

HGNC:6853

ORF Size (aa)

2844

ORF Size (bp)

2844 bp

RefSeq ID

NM_003954

RefSeq Synonyms

NM_003954, BC035576,

Species

human

UniGene ID

Hs.404183

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.