human MAFF shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MAFF.
shAAV-214795
AAV-h-MAFF-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MAFF (MAF bZIP transcription factor F). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hMafF; U-MAF
Description (Vector)
MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene.
Gene ID
23764
Gene Name (Vector)
MAF bZIP transcription factor F
Gene Symbol
MAFF
HGNC ID
HGNC:6780
ORF Size (aa)
495
RefSeq ID
NM_012323
RefSeq Synonyms
NM_012323, NM_001161574, NM_001161573, NM_001161572, BC067751, BC015037,
Species
human
UniGene ID
Hs.517617
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.