human LXN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LXN.
shAAV-214682
AAV-h-LXN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LXN (latexin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ECI; endogenous carboxypeptidase inhibitor; latexin; MUM; Protein MUM; TCI; tissue carboxypeptidase inhibitor
Description (eCommerce)
Latexin (LXN) is a hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA. LXN may play a role in inflammation. [taken from NCBI Entrez Gene (Gene ID: 56925)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BS40].
Description (Vector)
LXN encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases.
Gene ID
56925
Gene Name (eCommerce)
latexin
Gene Name (Vector)
latexin
Gene Symbol
LXN
HGNC ID
HGNC:13347
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
669
Protein Name (eCommerce)
Latexin
RefSeq ID
NM_020169
RefSeq Synonyms
NM_020169, BC008438, BC005346,
Research Areas
Immunology
Research Areas (Faceted)
immunology
Species
human
Target Sentence
Latexin (LXN) is a hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA. LXN may play a role in inflammation. [taken from NCBI Entrez Gene (Gene ID: 56925)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BS40].
UniGene ID
Hs.478067
UniProt ID (eCommerce)
Q9BS40
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.