human LRRN2 shRNA silencing AAV

Name
AAV-h-LRRN2-shRNA

Cat No
shAAV-214605

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human LRRN2.

shAAV-214605

AAV-h-LRRN2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LRRN2 (leucine rich repeat neuronal 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FIGLER7; GAC1; LRANK1; LRRN5

Description (Vector)

LRRN2 belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Gene ID

10446

Gene Name (Vector)

leucine rich repeat neuronal 2

Gene Symbol

LRRN2

HGNC ID

HGNC:16914

ORF Size (aa)

2142

ORF Size (bp)

2142 bp

RefSeq ID

NM_006338

RefSeq Synonyms

NM_201630, NM_006338, BC068541, BC034047,

Species

human

UniGene ID

Hs.26312

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.