human LGALS9 shRNA silencing AAV

Name 
AAV-h-LGALS9-shRNA
Cat No 
shAAV-213863
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LGALS9.

shAAV-213863
AAV-h-LGALS9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LGALS9 (galectin 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ecalectin; gal-9; galectin-9; HUAT; lectin, galactoside-binding, soluble, 9; LGALS9A; tumor antigen HOM-HD-21; urate transporter/channel protein
Description (eCommerce)
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-9 is an S-type lectin overexpressed in Hodgkin's disease tissue that plays a role in the pathogenesis of this disease and its associated immunodeficiency.[taken from NCBI Entrez Gene (Gene ID: 3965)].
Description (Vector)
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
Gene ID
3965
Gene Name (eCommerce)
galectin 9
Gene Name (Vector)
galectin 9
Gene Symbol
LGALS9
HGNC ID
HGNC:6570
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
972
Protein Name (eCommerce)
Galectin-9
RefSeq ID
NM_002308
RefSeq Synonyms
NM_009587, NM_002308, NM_001330163, BC110340, BC105944, BC105942,
Research Areas
NF-kB Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-9 is an S-type lectin overexpressed in Hodgkin's disease tissue that plays a role in the pathogenesis of this disease and its associated immunodeficiency.[taken from NCBI Entrez Gene (Gene ID: 3965)].
UniGene ID
Hs.81337
UniProt ID (eCommerce)
O00182

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.