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human LCE1A shRNA silencing AAV

Name 
AAV-h-LCE1A-shRNA
Cat No 
shAAV-213725
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human LCE1A.

shAAV-213725
AAV-h-LCE1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LCE1A (late cornified envelope 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LEP1
Description (Vector)
LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 (PubMed 15854049)). For further information on the LCE gene cluster, see GENE FAMILY below.(supplied by OMIM, Feb 2009)
Gene ID
353131
Gene Name (Vector)
late cornified envelope 1A
Gene Symbol
LCE1A
HGNC ID
HGNC:29459
ORF Size (aa)
333
RefSeq ID
NM_178348
RefSeq Synonyms
NM_178348, BC153155, BC146367,
Species
human
UniGene ID
Hs.534645

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.