human LCE1A Over-expression AAV

Name
AAV-h-LCE1A

Cat No
AAV-213725

Availability
4-5 weeks

This is an AAV expressing Human LCE1A.

AAV-213725

AAV-h-LCE1A

Ready-to-use AAV expressing Human LCE1A (late cornified envelope 1A). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LEP1

Description (Vector)

LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 (PubMed 15854049)). For further information on the LCE gene cluster, see GENE FAMILY below.(supplied by OMIM, Feb 2009)

Gene ID

353131

Gene Name (Vector)

late cornified envelope 1A

Gene Symbol

LCE1A

HGNC ID

HGNC:29459

ORF Size (aa)

333

RefSeq ID

NM_178348

RefSeq Synonyms

NM_178348, BC153155, BC146367,

Species

human

UniGene ID

Hs.534645

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.