human DTD1 Over-expression AAV

Name 
AAV-h-DTD1
Cat No 
AAV-207365
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DTD1.

AAV-207365
AAV-h-DTD1

Ready-to-use AAV expressing Human DTD1 (D-tyrosyl-tRNA deacylase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C20orf88; D-aminoacyl-tRNA deacylase 1; DNA-unwinding element-binding protein B; DTD; D-tyrosyl-tRNA deacylase 1 homolog; D-tyrosyl-tRNA(Tyr) deacylase 1; DUEB; DUE-B; gly-tRNA(Ala) deacylase; HARS2; histidyl-tRNA synthase-related; histidyl-tRNA synthetase 2; pqn-68
Description (eCommerce)
D-tyrosyl-tRNA(Tyr) deacylase 1 (DTD1) is an ATPase involved in DNA replication. It may facilitate loading of CDC45 onto pre-replication complexes. DTD1 may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TEA8].
Description (Vector)
DTD1 is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein is found in the cytoplasm.
Gene ID
92675
Gene Name (eCommerce)
D-tyrosyl-tRNA deacylase 1
Gene Name (Vector)
D-tyrosyl-tRNA deacylase 1
Gene Symbol
DTD1
HGNC ID
HGNC:16219
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
630
ORF Size (bp)
630 bp
Protein Name (eCommerce)
D-tyrosyl-tRNA(Tyr) deacylase 1
RefSeq ID
NM_080820
RefSeq Synonyms
NM_080820, NM_001318043, BC100926, BC100925, BC100924, BC100923, BC045167,
Research Areas
DNA Replication
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
D-tyrosyl-tRNA(Tyr) deacylase 1 (DTD1) is an ATPase involved in DNA replication. It may facilitate loading of CDC45 onto pre-replication complexes. DTD1 may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TEA8].
UniGene ID
Hs.659442
UniProt ID (eCommerce)
Q8TEA8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.