human KIF18B shRNA silencing AAV

Name 
AAV-h-KIF18B-shRNA
Cat No 
shAAV-213075
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KIF18B.

shAAV-213075
AAV-h-KIF18B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KIF18B (kinesin family member 18B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
kinesin-like protein KIF18B
Description (eCommerce)
Kinesin family member 18B (KIF18B) interacts with KIF2C. In a complex with KIF2C, KIF18B constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86Y91].
Gene ID
146909
Gene Name (eCommerce)
kinesin family member 18B
Gene Name (Vector)
kinesin family member 18B
Gene Symbol
KIF18B
HGNC ID
HGNC:27102
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2502
ORF Size (bp)
2502 bp
Protein Name (eCommerce)
Kinesin-like protein KIF18B
RefSeq ID
NM_001080443
RefSeq Synonyms
NM_001265577, NM_001264573, NM_001080443, BC144271, BC136590,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Kinesin family member 18B (KIF18B) interacts with KIF2C. In a complex with KIF2C, KIF18B constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q86Y91].
UniGene ID
Hs.135094
UniProt ID (eCommerce)
Q86Y91

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.