human DRAM Over-expression AAV

Name 
AAV-h-DRAM
Cat No 
AAV-207321
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DRAM1.

AAV-207321
AAV-h-DRAM

Ready-to-use AAV expressing Human DRAM1 (DNA damage regulated autophagy modulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DRAM
Description (Vector)
DRAM1 is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. DRAM1 has a pseudogene on chromosome 4.
Gene ID
55332
Gene Name (Vector)
DNA damage regulated autophagy modulator 1
Gene Symbol
DRAM1
HGNC ID
HGNC:25645
ORF Size (aa)
717
ORF Size (bp)
717 bp
RefSeq ID
NM_018370
RefSeq Synonyms
NM_018370, BC018435, BC013773,
Species
human
UniGene ID
Hs.525634

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.