human KIAA0406 shRNA silencing AAV

Name 
AAV-h-KIAA0406-shRNA
Cat No 
shAAV-212911
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human TTI1.

shAAV-212911
AAV-h-KIAA0406-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human TTI1 (TELO2 interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KIAA0406; Protein SMG10; smg-10; smg-10 homolog, nonsense mediated mRNA decay factor; Tel two interacting protein 1; TEL2-interacting protein 1 homolog; TELO2-interacting protein 1 homolog
Description (eCommerce)
TEL2-interacting protein 1 homolog (TTI1) promotes assembly, stabilizes, and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O43156].
Gene ID
9675
Gene Name (eCommerce)
TELO2 interacting protein 1
Gene Name (Vector)
TELO2 interacting protein 1
Gene Symbol
TTI1
HGNC ID
HGNC:29029
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3270
ORF Size (bp)
3270 bp
Protein Name (eCommerce)
TELO2-interacting protein 1 homolog
RefSeq ID
NM_014657
RefSeq Synonyms
NM_014657, NM_001303457, BC013755, BC013121,
Research Areas
DNA Damage/Repair
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
TEL2-interacting protein 1 homolog (TTI1) promotes assembly, stabilizes, and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O43156].
UniGene ID
Hs.655481
UniProt ID (eCommerce)
O43156

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.