human KCNK5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KCNK5.
shAAV-212748
AAV-h-KCNK5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KCNK5 (potassium two pore domain channel subfamily K member 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
acid-sensitive potassium channel protein TASK-2; K2p5.1; K2P5.1 potassium channel; KCNK5b; potassium channel subfamily K member 5; potassium channel, subfamily K, member 1 (TASK-2); potassium channel, subfamily, member 5 (KCNK5); potassium channel, two pore domain subfamily K, member 5; TASK2; TASK-2; TWIK-related acid-sensitive K(+) channel 2; TWIK-related acid-sensitive K+ channel 2
Description (eCommerce)
TWIK-related acid-sensitive K(+) channel 2 (TASK-2) is a pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95279].
Description (Vector)
KCNK5 encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport.
Gene ID
8645
Gene Name (eCommerce)
potassium two pore domain channel subfamily K member 5
Gene Name (Vector)
potassium two pore domain channel subfamily K member 5
Gene Symbol
KCNK5
HGNC ID
HGNC:6280
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1500
ORF Size (bp)
1500 bp
Protein Name (eCommerce)
Potassium channel subfamily K member 5
RefSeq ID
NM_003740
RefSeq Synonyms
NM_003740, BC069573, BC060793,
Research Areas
Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
TWIK-related acid-sensitive K(+) channel 2 (TASK-2) is a pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95279].
UniGene ID
Hs.444448
UniProt ID (eCommerce)
O95279
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.