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human IRF5 shRNA silencing AAV

Name 
AAV-h-IRF5-shRNA
Cat No 
shAAV-212410
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IRF5.

shAAV-212410
AAV-h-IRF5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IRF5 (interferon regulatory factor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
92
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SLEB10
Description (Vector)
IRF5 encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
Gene ID
3663
Gene Name (Vector)
interferon regulatory factor 5
Gene Symbol
IRF5
HGNC ID
HGNC:6120
ORF Size (aa)
1497
ORF Size (bp)
1497 bp
RefSeq ID
NM_001098629
RefSeq Synonyms
NM_032643, NM_001242452, NM_001098630, NM_001098629, NM_001098627, BC004201, BC004139,
Species
human
UniGene ID
Hs.521181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.