human IL33 shRNA silencing AAV

Name
AAV-h-IL33-shRNA

Cat No
shAAV-212189

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human IL33.

shAAV-212189

AAV-h-IL33-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL33 (interleukin 33). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV

Description (Vector)

IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4; MIM 147780). IL33 is a ligand for IL33R (IL1RL1; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 (PubMed 20926795)).(supplied by OMIM, Jan 2011)

Gene ID

90865

Gene Name (Vector)

interleukin 33

Gene Symbol

IL33

HGNC ID

HGNC:16028

ORF Size (aa)

813

ORF Size (bp)

813 bp

RefSeq ID

NM_033439

RefSeq Synonyms

NM_033439, NM_001314048, NM_001314047, NM_001314046, NM_001314045, NM_001314044, NM_001199641, NM_001199640, BC047085,

Species

human

UniGene ID

Hs.348390

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.