human IL1RAPL1 shRNA silencing AAV

Name
AAV-h-IL1RAPL1-shRNA

Cat No
shAAV-212112

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human IL1RAPL1.

shAAV-212112

AAV-h-IL1RAPL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL1RAPL1 (interleukin 1 receptor accessory protein like 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IL1R8; IL1RAPL; MRX10; MRX21; MRX34; OPHN4; TIGIRR-2

Description (Vector)

IL1RAPL1 is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. It is most closely related to interleukin 1 receptor accessory protein-like 2 (IL1RAPL2). This gene and IL1RAPL2 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation. Deletions and mutations in this gene were found in patients with mental retardation. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities.

Gene ID

11141

Gene Name (Vector)

interleukin 1 receptor accessory protein like 1

Gene Symbol

IL1RAPL1

HGNC ID

HGNC:5996

ORF Size (aa)

2091

ORF Size (bp)

2091 bp

RefSeq ID

NM_014271

RefSeq Synonyms

NM_014271, BC126347, BC126345, BC111918,

Species

human

UniGene ID

Hs.658912

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.