human IL17F shRNA silencing AAV

Name
AAV-h-IL17F-shRNA

Cat No
shAAV-212069

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human IL17F.

shAAV-212069

AAV-h-IL17F-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL17F (interleukin 17F). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CANDF6; IL-17F; ML-1; ML1

Description (Vector)

IL17F is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.

Gene ID

112744

Gene Name (Vector)

interleukin 17F

Gene Symbol

IL17F

HGNC ID

HGNC:16404

ORF Size (aa)

492

RefSeq ID

NM_052872

RefSeq Synonyms

NM_052872, BC070124,

Species

human

UniGene ID

Hs.272295

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.