human ICMT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ICMT.
shAAV-211756
AAV-h-ICMT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ICMT (isoprenylcysteine carboxyl methyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT
Description (Vector)
ICMT encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
Gene ID
23463
Gene Name (Vector)
isoprenylcysteine carboxyl methyltransferase
Gene Symbol
ICMT
HGNC ID
HGNC:5350
ORF Size (aa)
855
ORF Size (bp)
855 bp
RefSeq ID
NM_012405
RefSeq Synonyms
NM_012405, BC028168,
Species
human
UniGene ID
Hs.515688
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.