human HPN shRNA silencing AAV

Name
AAV-h-HPN-shRNA

Cat No
shAAV-211499

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HPN.

shAAV-211499

AAV-h-HPN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HPN (hepsin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

TMPRSS1

Description (Vector)

HPN encodes a type II transmembrane serine protease. The encoded protein has an extracellular region that consists of two domains, a catalytic serine protease domain and a non-catalytic scavenger receptor cysteine-rich domain. This protein may be involved in diverse cellular functions including blood coagulation, maintenance of cell morphology and the growth and progression of certain cancers, particularly prostate cancer. Alternative splicing results in multiple transcript variants.

Gene ID

3249

Gene Name (Vector)

hepsin

Gene Symbol

HPN

HGNC ID

HGNC:5155

ORF Size (aa)

1254

ORF Size (bp)

1254 bp

RefSeq ID

NM_182983

RefSeq Synonyms

NM_182983, NM_002151, BC025716,

Species

human

UniGene ID

Hs.182385

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.