human HOXB6 shRNA silencing AAV

Name 
AAV-h-HOXB6-shRNA
Cat No 
shAAV-211458
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HOXB6.

shAAV-211458
AAV-h-HOXB6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HOXB6 (homeobox B6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Hox-2.2; HOX2; HOX2B; HU-2
Description (Vector)
HOXB6 is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.
Gene ID
3216
Gene Name (Vector)
homeobox B6
Gene Symbol
HOXB6
HGNC ID
HGNC:5117
ORF Size (aa)
675
ORF Size (bp)
675 bp
RefSeq ID
NM_018952
RefSeq Synonyms
NM_018952, BC014651,
Species
human
UniGene ID
Hs.98428

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.