human HMHB1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HMHB1.
shAAV-211311
AAV-h-HMHB1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HMHB1 (histocompatibility minor HB-1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HB-1; HB-1Y; HLA-HB1
Description (Vector)
HMHB1 encodes one of the minor histocompatibility antigens, which play an important role in the induction of cytotoxic T lymphocyte (CTL) reactivity against leukemia after human histocompatibility leukocyte antigen (HLA)-identical allogeneic bone marrow transplantation (BMT). HMHB1 is only expressed in B cell acute lymphoblastic leukemia cells and Epstein-Barr virus-transformed B cells. The translation of this mRNA initiates at a non-AUG (CUG) codon.
Gene ID
57824
Gene Name (Vector)
histocompatibility minor HB-1
Gene Symbol
HMHB1
HGNC ID
HGNC:29677
ORF Size (aa)
126
RefSeq ID
NM_021182
RefSeq Synonyms
NM_021182, BC104413, BC104412,
Species
human
UniGene ID
Hs.158320
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.