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human HMHB1 Over-expression AAV

Name 
AAV-h-HMHB1
Cat No 
AAV-211311
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HMHB1.

AAV-211311
AAV-h-HMHB1

Ready-to-use AAV expressing Human HMHB1 (histocompatibility minor HB-1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HB-1; HB-1Y; HLA-HB1
Description (Vector)
HMHB1 encodes one of the minor histocompatibility antigens, which play an important role in the induction of cytotoxic T lymphocyte (CTL) reactivity against leukemia after human histocompatibility leukocyte antigen (HLA)-identical allogeneic bone marrow transplantation (BMT). HMHB1 is only expressed in B cell acute lymphoblastic leukemia cells and Epstein-Barr virus-transformed B cells. The translation of this mRNA initiates at a non-AUG (CUG) codon.
Gene ID
57824
Gene Name (Vector)
histocompatibility minor HB-1
Gene Symbol
HMHB1
HGNC ID
HGNC:29677
ORF Size (aa)
126
RefSeq ID
NM_021182
RefSeq Synonyms
NM_021182, BC104413, BC104412,
Species
human
UniGene ID
Hs.158320

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.