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human HARS2 shRNA silencing AAV

Name 
AAV-h-HARS2-shRNA
Cat No 
shAAV-210787
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HARS2.

shAAV-210787
AAV-h-HARS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HARS2 (histidyl-tRNA synthetase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HARSL; HARSR; HO3; PRLTS2
Description (Vector)
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes share a bidirectional promoter.
Gene ID
23438
Gene Name (Vector)
histidyl-tRNA synthetase 2, mitochondrial
Gene Symbol
HARS2
HGNC ID
HGNC:4817
ORF Size (aa)
1521
ORF Size (bp)
1521 bp
RefSeq ID
NM_012208
RefSeq Synonyms
NM_012208, NM_001278732, NM_001278731, BC014982, BC007680,
Species
human
UniGene ID
Hs.432560

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.