human GSG2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GSG2.
shAAV-210583
AAV-h-GSG2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GSG2 (germ cell associated 2, haspin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
germ cell associated 2, haspin; germ cell-specific gene 2 protein; GSG2; haploid germ cell-specific nuclear protein kinase; H-haspin; serine/threonine-protein kinase haspin
Description (eCommerce)
Hapsin is a serine-threonine protein kinase that was originally identified as a cDNA expressed specifically in mouse testicular germ cells. Haspin associates with the chromosomes, centrosomes, and spindle and is critical for proper chromosome alignment and segregation. Haspin is responsible for the phosphorylation of histone H3 at threonine 3.
Gene ID
83903
Gene Name (eCommerce)
histone H3 associated protein kinase
Gene Name (Vector)
germ cell associated 2, haspin
Gene Symbol
GSG2
HGNC ID
HGNC:19682
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2397
ORF Size (bp)
2397 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase haspin
RefSeq ID
NM_031965
RefSeq Synonyms
NM_031965, BC047457,
Research Areas
Cell Biology,Cell Cycle,Cytoskeleton,Histone Modification,Kinase/Phosphatase,Phosphatase,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,cell_biology
Species
human
Target Sentence
Hapsin is a serine-threonine protein kinase that was originally identified as a cDNA expressed specifically in mouse testicular germ cells. Haspin associates with the chromosomes, centrosomes, and spindle and is critical for proper chromosome alignment and segregation. Haspin is responsible for the phosphorylation of histone H3 at threonine 3.
UniGene ID
Hs.534059
UniProt ID (eCommerce)
Q8TF76
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.