human GSDMB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GSDMB.
shAAV-210574
AAV-h-GSDMB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GSDMB (gasdermin B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GSDML; PP4052; PRO2521
Description (Vector)
GSDMB encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.
Gene ID
55876
Gene Name (Vector)
gasdermin B
Gene Symbol
GSDMB
HGNC ID
HGNC:23690
ORF Size (aa)
1236
ORF Size (bp)
1236 bp
RefSeq ID
NM_018530
RefSeq Synonyms
NM_018530, NM_001165959, NM_001165958, NM_001042471, BC025682,
Species
human
UniGene ID
Hs.306777
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.