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human PDPK1 Adenovirus

Name 
Ad-h-PDPK1
Cat No 
ADV-219915
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PDPK1.

ADV-219915
Ad-h-PDPK1

Ready-to-use Adenovirus expressing Human PDPK1 (3-phosphoinositide dependent protein kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; hPDK1; PDK1; PDPK2; PDPK2P; PkB kinase like gene 1; PRO0461
Description (eCommerce)
PDK1 (3-phosphoinositide-dependent kinase-1) is a serine/threonine kinase that contains a PH domain for binding of phosphatidylinositols (PtdIns). PDK1 phosphorylates PKB/AKT in response to agonist stimulation of phosphoinositide 3-kinases (PI3Ks). Stimulation of PI3Ks generates specific inositol lipids that are important for activation of PDK1. PDK1 may also be responsible for phosphorylating PKA, PKC-zeta, RPS6KA1, and RPS6KB1.
Gene ID
5170
Gene Name (eCommerce)
3-phosphoinositide dependent protein kinase 1
Gene Name (Vector)
3-phosphoinositide dependent protein kinase 1
Gene Symbol
PDPK1
HGNC ID
HGNC:8816
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1671
ORF Size (bp)
1671 bp
Protein Name (eCommerce)
3-phosphoinositide-dependent protein kinase 1
RefSeq ID
NM_002613
RefSeq Synonyms
NM_031268, NM_002613, NM_001261816, BC033494, BC012103, BC006339,
Research Areas
Angiogenesis,Apoptosis,B-cell Receptor Signaling,BDNF Signaling,Cancer,Cardiac Development,Cardiac Hypertrophy,Cardiology,Cardiovascular,CD95/FAS Signaling,Cell Cycle,Cytoskeleton,EGFR Signaling,EGFR Signaling in Cancer,EPO Signaling,Fc Receptor Signaling,FGF Signaling,Glioma,GPCR Signaling,HGF Signaling,Host-Virus Interactions,Hypoxia,IGF-1 Signaling,Immunology,Innate Immunity,Insulin Signaling,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,Lung Cancer,mTOR Signaling,Neurobiology,NF-kB Signaling,NGF Signaling,PDGF Signaling,PI3K/Akt Signaling,PI3K-AKT Signaling in Cancer,Prostate Cancer,SCF-KIT Signaling,Signal Transduction,T-cell Receptor Signaling,TGF-beta Signaling,Toll-like Receptor Signaling,Transcription Factor/Regulator,TRKA Signaling,TSH Signaling,VEGF Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,immunology,infectious_disease,neurobiology,signal_transduction,stem_cell_biology,transcription_translation
Species
human
Target Sentence
PDK1 (3-phosphoinositide-dependent kinase-1) is a serine/threonine kinase that contains a PH domain for binding of phosphatidylinositols (PtdIns). PDK1 phosphorylates PKB/AKT in response to agonist stimulation of phosphoinositide 3-kinases (PI3Ks). Stimulation of PI3Ks generates specific inositol lipids that are important for activation of PDK1. PDK1 may also be responsible for phosphorylating PKA, PKC-zeta, RPS6KA1, and RPS6KB1.
UniGene ID
Hs.459691
UniProt ID (eCommerce)
O15530

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.