human GRIN2B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GRIN2B.
shAAV-210524
AAV-h-GRIN2B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EIEE27; GluN2B; hNR3; MRD6; NMDAR2B; NR2B
Description (Vector)
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
Gene ID
2904
Gene Name (Vector)
glutamate ionotropic receptor NMDA type subunit 2B
Gene Symbol
GRIN2B
HGNC ID
HGNC:4586
ORF Size (aa)
4455
ORF Size (bp)
4455 bp
RefSeq ID
NM_000834
RefSeq Synonyms
NM_000834, BC113620, BC113618,
Species
human
UniGene ID
Hs.654430
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.

