human GPR77 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human C5AR2.
shAAV-210397
AAV-h-GPR77-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human C5AR2 (complement component 5a receptor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C5L2; GPF77; GPR77
Description (Vector)
The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 (PubMed 16204243)).(supplied by OMIM, Mar 2008)
Gene ID
27202
Gene Name (Vector)
complement component 5a receptor 2
Gene Symbol
C5AR2
HGNC ID
HGNC:4527
ORF Size (aa)
1014
RefSeq ID
NM_018485
RefSeq Synonyms
NM_018485, NM_001271750, NM_001271749, BC067480, BC067479, BC067478, BC067477,
Species
human
UniGene ID
Hs.534412
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.