human GPR44 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PTGDR2.
shAAV-210356
AAV-h-GPR44-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PTGDR2 (prostaglandin D2 receptor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD294; CRTH2; DL1R; DP2; GPR44
Description (Vector)
PTGDR2 encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
Gene ID
11251
Gene Name (Vector)
prostaglandin D2 receptor 2
Gene Symbol
PTGDR2
HGNC ID
HGNC:4502
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_004778
RefSeq Synonyms
NM_004778, BC096841,
Species
human
UniGene ID
Hs.299567
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.