human GM2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GM2A.
shAAV-210031
AAV-h-GM2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GM2A (GM2 ganglioside activator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GM2-AP; SAP-3
Description (Vector)
GM2A encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
Gene ID
2760
Gene Name (Vector)
GM2 ganglioside activator
Gene Symbol
GM2A
HGNC ID
HGNC:4367
ORF Size (aa)
582
RefSeq ID
NM_000405
RefSeq Synonyms
NM_001167607, NM_000405, BC009273,
Species
human
UniGene ID
Hs.483873
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.