human FZD7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FZD7.
shAAV-209469
AAV-h-FZD7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FZD7 (frizzled class receptor 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FzE3
Description (Vector)
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Gene ID
8324
Gene Name (Vector)
frizzled class receptor 7
Gene Symbol
FZD7
HGNC ID
HGNC:4045
ORF Size (aa)
1725
ORF Size (bp)
1725 bp
RefSeq ID
NM_003507
RefSeq Synonyms
NM_003507, BC015915,
Species
human
UniGene ID
Hs.173859
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.