human FZD7 Adenovirus

Name
Ad-h-FZD7

Cat No
ADV-209469

Availability
4-5 weeks

This is an Adenovirus expressing Human FZD7.

ADV-209469

Ad-h-FZD7

Ready-to-use Adenovirus expressing Human FZD7 (frizzled class receptor 7). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

FzE3

Description (Vector)

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Gene ID

8324

Gene Name (Vector)

frizzled class receptor 7

Gene Symbol

FZD7

HGNC ID

HGNC:4045

ORF Size (aa)

1725

ORF Size (bp)

1725 bp

RefSeq ID

NM_003507

RefSeq Synonyms

NM_003507, BC015915,

Species

human

UniGene ID

Hs.173859

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.