human FREQ shRNA silencing AAV

Name
AAV-h-FREQ-shRNA

Cat No
shAAV-209308

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NCS1.

shAAV-209308

AAV-h-FREQ-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NCS1 (neuronal calcium sensor 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FLUP; FREQ

Description (Vector)

NCS1 is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

23413

Gene Name (Vector)

neuronal calcium sensor 1

Gene Symbol

NCS1

HGNC ID

HGNC:3953

ORF Size (aa)

573

RefSeq ID

NM_014286

RefSeq Synonyms

NM_014286, NM_001128826, BC004856,

Species

human

UniGene ID

Hs.642946

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.