human FCGR2B shRNA silencing AAV

Name 
AAV-h-FCGR2B-shRNA
Cat No 
shAAV-208857
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human FCGR2B.

shAAV-208857
AAV-h-FCGR2B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human FCGR2B (Fc fragment of IgG receptor IIb). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD32; CD32B; FCG2; FCGR2; IGFR2
Description (Vector)
FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
2213
Gene Name (Vector)
Fc fragment of IgG receptor IIb
Gene Symbol
FCGR2B
HGNC ID
HGNC:3618
ORF Size (aa)
876
ORF Size (bp)
876 bp
RefSeq ID
NM_004001
RefSeq Synonyms
NM_004001, NM_001190828, NM_001002275, NM_001002274, NM_001002273, BC148273, BC146678, BC141826, BC031992,
Species
human
UniGene ID
Hs.654395

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.