human FBLIM1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FBLIM1.
shAAV-208734
AAV-h-FBLIM1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FBLIM1 (filamin binding LIM protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAL; FBLP-1; FBLP1
Description (Vector)
FBLIM1 encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
54751
Gene Name (Vector)
filamin binding LIM protein 1
Gene Symbol
FBLIM1
HGNC ID
HGNC:24686
ORF Size (aa)
1122
ORF Size (bp)
1122 bp
RefSeq ID
NM_017556
RefSeq Synonyms
NM_017556, NM_001024216, NM_001024215, BC019895,
Species
human
UniGene ID
Hs.530101
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.