human FAM62A shRNA silencing AAV

Name
AAV-h-FAM62A-shRNA

Cat No
shAAV-208605

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ESYT1.

shAAV-208605

AAV-h-FAM62A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ESYT1 (extended synaptotagmin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

E-Syt1; extended synaptotagmin like protein 1; extended synaptotagmin protein 1; extended synaptotagmin-1; FAM62A; family with sequence similarity 62 (C2 domain containing), member A; MBC2; membrane-bound C2 domain-containing protein

Description (eCommerce)

Extended synaptotagmin-like protein 1 (E-Syt1) is a member of a family of proteins, E-Syts, that may function as Ca(2+)-regulated membrane proteins. E-Syt1 is a multi-pass membrane protein that localizes to intracellular membranes and contains 5 C2 domains.

Gene ID

23344

Gene Name (eCommerce)

extended synaptotagmin 1

Gene Name (Vector)

extended synaptotagmin 1

Gene Symbol

ESYT1

HGNC ID

HGNC:29534

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3315

ORF Size (bp)

3315 bp

Protein Name (eCommerce)

Extended synaptotagmin-1

RefSeq ID

NM_015292

RefSeq Synonyms

NM_015292, NM_001184796, BC004998,

Research Areas

EGFR Signaling,Signal Transduction

Research Areas (Faceted)

signal_transduction

Species

human

Target Sentence

Extended synaptotagmin-like protein 1 (E-Syt1) is a member of a family of proteins, E-Syts, that may function as Ca(2+)-regulated membrane proteins. E-Syt1 is a multi-pass membrane protein that localizes to intracellular membranes and contains 5 C2 domains.

UniGene ID

Hs.632729

UniProt ID (eCommerce)

Q9BSJ8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.