human ESM1 shRNA silencing AAV

Name 
AAV-h-ESM1-shRNA
Cat No 
shAAV-208108
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ESM1.

shAAV-208108
AAV-h-ESM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ESM1 (endothelial cell specific molecule 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
endocan
Description (Vector)
ESM1 encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
11082
Gene Name (Vector)
endothelial cell specific molecule 1
Gene Symbol
ESM1
HGNC ID
HGNC:3466
ORF Size (aa)
555
ORF Size (bp)
555 bp
RefSeq ID
NM_007036
RefSeq Synonyms
NM_007036, NM_001135604, BC011989,
Species
human
UniGene ID
Hs.129944

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.