human ERF shRNA silencing AAV

Name 
AAV-h-ERF-shRNA
Cat No 
shAAV-208067
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ERF.

shAAV-208067
AAV-h-ERF-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ERF (ETS2 repressor factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CHYTS; CRS4; ETS domain-containing transcription factor ERF; Ets2 repressor factor; PE2; PE-2
Description (eCommerce)
Ets2 repressor factor (ERF) is a member of the ETS (e26 transformation specific sequence) family of proteins. ETS family members bear an ETS-domain, a DNA binding domain that recognizes purine-rich sequences. ERF functions as a transcriptional repressor and is an effector of the Erk signaling pathway.
Description (Vector)
Members of the ETS family of transcription factors, such as ERF, regulate cell proliferation and differentiation. They share a highly conserved DNA-binding domain, the ETS domain, that recognizes the sequence GGAA/T (de Castro et al., 1997 (PubMed 9192842)). For further information on ETS transcription factors, see ETS1 (MIM 164720).(supplied by OMIM, Mar 2008)
Gene ID
2077
Gene Name (eCommerce)
ETS2 repressor factor
Gene Name (Vector)
ETS2 repressor factor
Gene Symbol
ERF
HGNC ID
HGNC:3444
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1647
ORF Size (bp)
1647 bp
Protein Name (eCommerce)
ETS domain-containing transcription factor ERF
RefSeq ID
NM_006494
RefSeq Synonyms
NM_006494, NM_001312656, NM_001308402, NM_001301035, BC022231,
Research Areas
Cell Cycle,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Ets2 repressor factor (ERF) is a member of the ETS (e26 transformation specific sequence) family of proteins. ETS family members bear an ETS-domain, a DNA binding domain that recognizes purine-rich sequences. ERF functions as a transcriptional repressor and is an effector of the Erk signaling pathway.
UniGene ID
Hs.655969
UniProt ID (eCommerce)
P50548

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.