human EPHX1 shRNA silencing AAV

Name 
AAV-h-EPHX1-shRNA
Cat No 
shAAV-207999
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human EPHX1.

shAAV-207999
AAV-h-EPHX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EPHX1 (epoxide hydrolase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EPHX; EPOX; HYL1; MEH
Description (Vector)
Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
2052
Gene Name (Vector)
epoxide hydrolase 1
Gene Symbol
EPHX1
HGNC ID
HGNC:3401
ORF Size (aa)
1368
ORF Size (bp)
1368 bp
RefSeq ID
NM_000120
RefSeq Synonyms
NM_001291163, NM_001136018, NM_000120, BC095430, BC008291, BC003567,
Species
human
UniGene ID
Hs.89649

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.