human DES Over-expression AAV

Name 
AAV-h-DES
Cat No 
AAV-206889
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DES.

AAV-206889
AAV-h-DES

Ready-to-use AAV expressing Human DES (desmin). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CSM1; CSM2; LGMD2R
Description (Vector)
DES encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.
Gene ID
1674
Gene Name (Vector)
desmin
Gene Symbol
DES
HGNC ID
HGNC:2770
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
RefSeq ID
NM_001927
RefSeq Synonyms
NM_001927, BC032116,
Species
human
UniGene ID
Hs.594952

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.