human EFNA1 shRNA silencing AAV

Name
AAV-h-EFNA1-shRNA

Cat No
shAAV-207630

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human EFNA1.

shAAV-207630

AAV-h-EFNA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human EFNA1 (ephrin A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

B61; ECKLG; EFL1; EPLG1; LERK-1; LERK1; TNFAIP4

Description (Vector)

EFNA1 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. EFNA1 encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.

Gene ID

1942

Gene Name (Vector)

ephrin A1

Gene Symbol

EFNA1

HGNC ID

HGNC:3221

ORF Size (aa)

618

ORF Size (bp)

618 bp

RefSeq ID

NM_004428

RefSeq Synonyms

NM_182685, NM_004428, BC095432, BC032698,

Species

human

UniGene ID

Hs.516664

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.