Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human DYNC1LI1 shRNA silencing AAV

Name 
AAV-h-DYNC1LI1-shRNA
Cat No 
shAAV-207464
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DYNC1LI1.

shAAV-207464
AAV-h-DYNC1LI1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cytoplasmic dynein 1 light intermediate chain 1; DLC-A; DNCLI1; dynein light chain A; dynein light intermediate chain 1, cytosolic; dynein, cytoplasmic, light intermediate polypeptide 1; LIC1
Description (eCommerce)
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. It may play a role in binding dynein to membranous organelles or chromosomes and is probably involved in the microtubule-dependent transport of pericentrin. DYNC1LI1 Is required for progress through the spindle assembly checkpoint [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6G9].
Gene ID
51143
Gene Name (eCommerce)
dynein cytoplasmic 1 light intermediate chain 1
Gene Name (Vector)
dynein cytoplasmic 1 light intermediate chain 1
Gene Symbol
DYNC1LI1
HGNC ID
HGNC:18745
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1572
ORF Size (bp)
1572 bp
Protein Name (eCommerce)
Cytoplasmic dynein 1 light intermediate chain 1
RefSeq ID
NM_016141
RefSeq Synonyms
NM_016141, NM_001329135, BC131620,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Host-Virus Interactions,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,infectious_disease
Species
human
Target Sentence
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. It may play a role in binding dynein to membranous organelles or chromosomes and is probably involved in the microtubule-dependent transport of pericentrin. DYNC1LI1 Is required for progress through the spindle assembly checkpoint [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y6G9].
UniGene ID
Hs.529495
UniProt ID (eCommerce)
Q9Y6G9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.