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human DNAJC5 shRNA silencing AAV

Name 
AAV-h-DNAJC5-shRNA
Cat No 
shAAV-207172
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DNAJC5.

shAAV-207172
AAV-h-DNAJC5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAJC5 (DnaJ heat shock protein family (Hsp40) member C5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLN4; CLN4B; CSP; DNAJC5A; mir-941-2; mir-941-3; mir-941-4; mir-941-5; NCL
Description (Vector)
DNAJC5 is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8.
Gene ID
80331
Gene Name (Vector)
DnaJ heat shock protein family (Hsp40) member C5
Gene Symbol
DNAJC5
HGNC ID
HGNC:16235
ORF Size (aa)
597
ORF Size (bp)
597 bp
RefSeq ID
NM_025219
RefSeq Synonyms
NM_025219, BC053642,
Species
human
UniGene ID
Hs.164419

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.