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human DNAI1 shRNA silencing AAV

Name 
AAV-h-DNAI1-shRNA
Cat No 
shAAV-207114
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DNAI1.

shAAV-207114
AAV-h-DNAI1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAI1 (dynein axonemal intermediate chain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CILD1; DIC1; ICS1; PCD
Description (Vector)
The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome.
Gene ID
27019
Gene Name (Vector)
dynein axonemal intermediate chain 1
Gene Symbol
DNAI1
HGNC ID
HGNC:2954
ORF Size (aa)
2100
ORF Size (bp)
2100 bp
RefSeq ID
NM_012144
RefSeq Synonyms
NM_012144, NM_001281428, BC030583,
Species
human
UniGene ID
Hs.112667

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.