human DNAI1 Adenovirus
This is an Adenovirus expressing Human DNAI1.
ADV-207114
Ad-h-DNAI1
Ready-to-use Adenovirus expressing Human DNAI1 (dynein axonemal intermediate chain 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CILD1; DIC1; ICS1; PCD
Description (Vector)
The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome.
Gene ID
27019
Gene Name (Vector)
dynein axonemal intermediate chain 1
Gene Symbol
DNAI1
HGNC ID
HGNC:2954
ORF Size (aa)
2100
ORF Size (bp)
2100 bp
RefSeq ID
NM_012144
RefSeq Synonyms
NM_012144, NM_001281428, BC030583,
Species
human
UniGene ID
Hs.112667
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.