human CYP4B1 shRNA silencing AAV

Name
AAV-h-CYP4B1-shRNA

Cat No
shAAV-206511

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CYP4B1.

shAAV-206511

AAV-h-CYP4B1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CYP4B1 (cytochrome P450 family 4 subfamily B member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CYPIVB1; P-450HP

Description (Vector)

CYP4B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined. Two transcript variants encoding slightly different isoforms have been found for this gene.

Gene ID

1580

Gene Name (Vector)

cytochrome P450 family 4 subfamily B member 1

Gene Symbol

CYP4B1

HGNC ID

HGNC:2644

ORF Size (aa)

1539

ORF Size (bp)

1539 bp

RefSeq ID

NM_000779

RefSeq Synonyms

NM_001319163, NM_001319162, NM_001319161, NM_001099772, NM_000779, BC017758,

Species

human

UniGene ID

Hs.436317

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.