human CYP2A13 shRNA silencing AAV

Name
AAV-h-CYP2A13-shRNA

Cat No
shAAV-206472

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CYP2A13.

shAAV-206472

AAV-h-CYP2A13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CYP2A13 (cytochrome P450 family 2 subfamily A member 13). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CPAD; CYP2A; CYPIIA13

Description (Vector)

CYP2A13 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. CYP2A13 is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Gene ID

1553

Gene Name (Vector)

cytochrome P450 family 2 subfamily A member 13

Gene Symbol

CYP2A13

HGNC ID

HGNC:2608

ORF Size (aa)

1482

ORF Size (bp)

1482 bp

RefSeq ID

NM_000766

RefSeq Synonyms

NM_000766, BC153000, BC148422,

Species

human

UniGene ID

Hs.567252

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.